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Mr Kevin van Zandvoort

Research Fellow

United Kingdom

I am an infectious disease epidemiologist and modeller with experience in study design, field data collection, and data analysis, including statistical and transmission modelling. I have been working at the School since completing my MSc in Epidemiology here in 2017. Prior to this, I worked as a webdeveloper in the Netherlands.

 

My research primarily focusses on pneumococcal vaccination strategies:

  1. Identifying pneumococcal vaccination strategies in humanitarian crises
    I am the main researcher on the ESPICC and EEPICC studies exploring effective PCV vaccination strategies that could feasibly be used in humanitarian crises. We are currently evaluating the effectiveness of a PCV campaign in children <5y living in a camp for displaced people in Somaliland, with the vaccination strategy informed by mathematical modelling and primary data collection. This short animated video and this conference talk summarize the main modelled results.

  2. Understanding the effect of reduced-dose routine vaccination schedules
    I am the main modeller on a cluster randomized controlled trial in Vietnam evaluating the effect of reduced-dose routine PCV schedules (0p+1 and 1p+1) relative to currently recommended 3-dose schedules (3p+0 and 2p+1). We are currently trying to understand whether the potential increased health burden when switching to a 2-dose schedule may be justified by the substantial cost savings from removing one dose. Preliminary results were presented in this webinar.

  3. Modelling other pneumococcal vaccination projects
    My generalizable compartmental metapopulation PCV transmission model can easily be adapted to other settings, using any number of populations, vaccination schedules, and age groups. I work with other collaborators using the model to analyse different pneumococcal projects, including the PVS trial in the Gambia (led by the MRC unit the Gambia), fPCV trial in Niger (led by Epicentre), and other studies in Fiji, Somaliland, and China.

  4. Social contact studies
    In addition to my vaccination work, I have been involved in the design, implementation, and analysis of several social contact studies. These include the CoMix study measuring contact patterns using the Covid-19 pandemic, the ongoing UK social contact study, and contact studies in the Gambia, Niger, informal settlements in Kenya, and a camp for displaced people in Somaliland.

Affiliations

Department of Infectious Disease Epidemiology and Dynamics
Faculty of Epidemiology and Population Health

Centres

Centre for Mathematical Modelling of Infectious Diseases
Vaccine Centre
Health in Humanitarian Crises Centre

Teaching

I co-organize the Health Data Management module on the MSc Health Data Science, where I teach on topics such as database interface libraries, data pipelines, and automated report generation. I also teach about infectious disease modelling on several other modules.

Research

I am particularly interested in optimizing vaccination strategies for populations affected by humanitarian crises. In these settings, where data is often scarce and opportunities for primary data collection are limited, mathematical modelling can play a critical role. Coupled with minimal primary data collection, models could capture and understand unique local transmission dynamics, and better inform and refine vaccination strategies that meet the unique needs of these populations.

Selected Publications

Social contacts and other risk factors for respiratory infections among internally displaced people in Somaliland.
VAN ZANDVOORT, K; Bobe, MO; Hassan, AI; Abdi, MI; Ahmed, MS; Soleman, SM; Warsame, MY; Wais, MA; Diggle, E; MCGOWAN, CR; Satzke, C; Mulholland, K; Egeh, MM; Hassan, MM; Hergeeye, MA; EGGO, RM; CHECCHI, F; FLASCHE, S;
2022
Epidemics
The impact of population-wide rapid antigen testing on SARS-CoV-2 prevalence in Slovakia.
PAVELKA, M; Van-Zandvoort, K; ABBOTT, S; SHERRATT, K; Majdan, M; CMMID COVID-19 working group,; Inštitút Zdravotných Analýz,; Jarčuška, P; Krajčí, M; FLASCHE, S; FUNK, S;
2021
Science (New York, N.Y.)
Quantifying the impact of physical distance measures on the transmission of COVID-19 in the UK.
JARVIS, CI; VAN ZANDVOORT, K; Gimma, A; PREM, K; CMMID COVID-19 working group,; KLEPAC, P; Rubin, GJ; EDMUNDS, WJ;
2020
BMC medicine
Response strategies for COVID-19 epidemics in African settings: a mathematical modelling study.
VAN ZANDVOORT, K; JARVIS, CI; PEARSON, CA B; DAVIES, NG; CMMID COVID-19 working group,; RATNAYAKE, R; RUSSELL, TW; KUCHARSKI, AJ; JIT, M; FLASCHE, S; EGGO, RM; CHECCHI, F;
2020
BMC Medicine
Pneumococcal conjugate vaccine use during humanitarian crises.
VAN ZANDVOORT, K; CHECCHI, F; Diggle, E; EGGO, RM; Gadroen, K; Mulholland, K; MCGOWAN, CR; LE POLAIN DE WAROUX, O; RAO, VB; Satzke, C; FLASCHE, S;
2019
Vaccine
Efficacy of live oral rotavirus vaccines by duration of follow-up: a meta-regression of randomised controlled trials.
CLARK, A; VAN ZANDVOORT, K; FLASCHE, S; SANDERSON, C; Bines, J; Tate, J; Parashar, U; JIT, M;
2019
LANCET INFECTIOUS DISEASES
Mortality reduction benefits and intussusception risks of rotavirus vaccination in 135 low-income and middle-income countries: a modelling analysis of current and alternative schedules.
CLARK, A; Tate, J; Parashar, U; JIT, M; Hasso-Agopsowicz, M; Henschke, N; Lopman, B; VAN ZANDVOORT, K; Pecenka, C; FINE, P; SANDERSON, C;
2017
The Lancet Global Health
Thinking fast and slow: the urgency of crisis response must not lead us to overlook chronic needs such as tuberculosis.
Dodd, PJ; VAN ZANDVOORT, K; Checchi, F; Khan, U; Haqmal, M; KHAN, P; MCQUAID, CF;
2025
BMJ global health
Social contacts and mixing patterns in rural Gambia.
OSEI, I; Mendy, E; VAN ZANDVOORT, K; Young, B; Jobe, O; Sarwar, G; Mohammed, NI; BRUCE, J; GREENWOOD, B; FLASCHE, S; MACKENZIE, GA;
2025
BMC infectious diseases
Pre-vaccination carriage prevalence of Streptococcus pneumoniae serotypes among internally displaced people in Somaliland: a cross-sectional study.
VAN ZANDVOORT, K; Hassan, AI; Bobe, MO; Pell, CL; Ahmed, MS; Ortika, BD; Ibrahim, S; Abdi, MI; Karim, MA; EGGO, RM; Ali, SY; Hinds, J; Soleman, SM; Cummings, R; McGowan, CR; Mulholland, EK; Hergeye, MA; Satzke, C; CHECCHI, F; Flasche, S;
2024
Pneumonia (Nathan Qld.)
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